Order DNA Tests

Disease Info

Keyword Site search

EXPLANATION OF ADULT ONSET NEUROPATHY RESULTS

NORMAL

This dog has tested normal (or clear) for the mutation known to cause Adult Onset Neuropathy (AN) in English Cocker Spaniels and Field Spaniels. It is not at risk for developing this form of the disease. It can only transmit a normal gene to offspring, and current information indicates that dogs with this result can be bred to a dog with any DNA test result without risk of producing affected offspring.

CARRIER

This dog has tested as a carrier for the mutation known to cause Adult Onset Neuropathy (AN) in English Cocker Spaniels and Field Spaniels. There is no evidence at present that these dogs will develop clinical symptoms of Adult Onset Neuropathy (AN). It may transmit either a normal gene or a mutated/affected gene to potential offspring. To avoid risk of producing an affected puppy, these dogs should only be bred to mates which have been DNA-tested normal.

AFFECTED/AT RISK

This dog has 2 mutated copies of the gene known to cause Adult Onset Neuropathy (AN) in English Cocker Spaniels and Field Spaniels and is at risk for developing clinical symptoms of AN at some point in its lifetime, usually after 7 years of age. The clinical signs will progress slowly over 2-4 years, similar to degenerative myelopathy (DM), but the disease course is more gradual and of longer duration.  

*Note – although clinical signs are similar to DM, all affected dogs studied to date have tested clear for the mutation that causes DM.

Partners

Canine Health Information Center (CHIC)

Canine Health Foundation

Morris Animal Foundation

Animal Health Trust

Join us on the OFA Facebook page